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Ghrelin transport across the blood–brain barrier can occur independently of the growth hormone secretagogue receptor

OBJECTIVE: The blood–brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB. Once present in the CNS, ghrelin can act in the hypothalamus to regulate f...

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Detalles Bibliográficos
Autores principales: Rhea, Elizabeth M., Salameh, Therese S., Gray, Sarah, Niu, Jingjing, Banks, William A., Tong, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308033/
https://www.ncbi.nlm.nih.gov/pubmed/30293893
http://dx.doi.org/10.1016/j.molmet.2018.09.007