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Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

OBJECTIVES: Insulin receptor (IR)-mediated signaling is involved in the regulation of pluripotent stem cells; however, its direct effects on regulating the maintenance of pluripotency and lineage development are not fully understood. The main objective of this study is to understand the role of IR s...

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Detalles Bibliográficos
Autores principales: Gupta, Manoj K., De Jesus, Dario F., Kahraman, Sevim, Valdez, Ivan A., Shamsi, Farnaz, Yi, Lian, Swensen, Adam C., Tseng, Yu-Hua, Qian, Wei-Jun, Kulkarni, Rohit N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308035/
https://www.ncbi.nlm.nih.gov/pubmed/30316806
http://dx.doi.org/10.1016/j.molmet.2018.09.003