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Validation of a novel single‐drop rapid human leukocyte antigen‐DQ2/‐DQ8 typing method to identify subjects susceptible to celiac disease

BACKGROUND AND AIM: Human leukocyte antigen (HLA)‐DQ2 and/or ‐DQ8 is an essential risk factor for celiac disease (CD). About 90–95% of patients with CD carry HLA‐DQ2/‐DQ8 alleles, and HLA‐DQ typing is considered an additional diagnostic test. Conventional polymerase chain reaction (PCR)‐based HLA‐DQ...

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Detalles Bibliográficos
Autores principales: Verma, Anil K, Singh, Alka, Gatti, Simona, Lionetti, Elena, Galeazzi, Tiziana, Monachesi, Chiara, Franceschini, Elisa, Ahuja, Vineet, Catassi, Carlo, Makharia, Govind K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308057/
https://www.ncbi.nlm.nih.gov/pubmed/30619943
http://dx.doi.org/10.1002/jgh3.12090