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Rs3212986 polymorphism, a possible biomarker to predict smoking‐related lung cancer, alters DNA repair capacity via regulating ERCC1 expression

Single nucleotide polymorphisms (SNPs) in 3′UTR of key DNA repair enzyme genes are associated with inter‐individual differences of DNA repair capacity (DRC) and susceptibility to a variety of human malignancies such as lung cancer. In this study, seven candidate SNPs in 3′UTR of DRC‐related genes in...

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Detalles Bibliográficos
Autores principales: Yu, Tao, Xue, Ping, Cui, Su, Zhang, Liang, Zhang, Guopei, Xiao, Mingyang, Zheng, Xiao, Zhang, Qianye, Cai, Yuan, Jin, Cuihong, Yang, Jinghua, Wu, Shengwen, Lu, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308093/
https://www.ncbi.nlm.nih.gov/pubmed/30453383
http://dx.doi.org/10.1002/cam4.1842