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CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion

Dendritic cell (DC) expression of CD103, the α subunit of αEβ7 integrin, is thought to enable DC interactions with E-cadherin-expressing gastrointestinal epithelia for improved mucosal immunosurveillance. In the stomach, efficient DC surveillance of the epithelial barrier is crucial for the inductio...

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Detalles Bibliográficos
Autores principales: Swain, Steve, Roe, Mandi M., Sebrell, Thomas A., Sidar, Barkan, Dankoff, Jennifer, VanAusdol, Rachel, Smythies, Lesley E., Smith, Phillip D., Bimczok, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308147/
https://www.ncbi.nlm.nih.gov/pubmed/30622531
http://dx.doi.org/10.3389/fimmu.2018.02989