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Anticancer Activity of the Goat Antimicrobial Peptide ChMAP-28

Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was examined against five cancer and two normal human cell lines. ChMAP-28 has the amino acid sequence GRFKRFRKKLKRLWHKVGPFVGPILHY and is homologous to other α-helical mammalian antimicrobial peptides. Ch...

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Detalles Bibliográficos
Autores principales: Emelianova, Anna A., Kuzmin, Denis V., Panteleev, Pavel V., Sorokin, Maxim, Buzdin, Anton A., Ovchinnikova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308165/
https://www.ncbi.nlm.nih.gov/pubmed/30622471
http://dx.doi.org/10.3389/fphar.2018.01501