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The Application of ATR-FTIR Spectroscopy and the Reversible DNA Conformation as a Sensor to Test the Effectiveness of Platinum(II) Anticancer Drugs

Platinum(II) complexes have been found to be effective against cancer cells. Cisplatin curbs cell replication by interacting with the deoxyribonucleic acid (DNA), reducing cell proliferation and eventually leading to cell death. In order to investigate the ability of platinum complexes to affect can...

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Detalles Bibliográficos
Autores principales: Al-Jorani, Khansa, Rüther, Anja, Martin, Miguela, Haputhanthri, Rukshani, Deacon, Glen B., Li, Hsiu Lin, Wood, Bayden R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308638/
https://www.ncbi.nlm.nih.gov/pubmed/30563229
http://dx.doi.org/10.3390/s18124297