Highly sensitive LC–MS/MS method to estimate doxepin and its metabolite nordoxepin in human plasma for a bioequivalence study

A selective, sensitive and rugged liquid chromatography–tandem mass spectrometry (LC–MS/MS) assay has been developed for the simultaneous determination of doxepin (Dox) and its pharmacologically active metabolite, nordoxepin (NDox) in human plasma. The analytes and their internal standards (IS) were...

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Detalles Bibliográficos
Autores principales: Patel, Nirav P., Sanyal, Mallika, Sharma, Naveen, Patel, Dinesh S., Shrivastav, Pranav S., Patel, Bhavin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308917/
https://www.ncbi.nlm.nih.gov/pubmed/30595944
http://dx.doi.org/10.1016/j.jpha.2017.06.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308917/
https://www.ncbi.nlm.nih.gov/pubmed/30595944
http://dx.doi.org/10.1016/j.jpha.2017.06.004

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