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Evaluation of top-down mass spectral identification with homologous protein sequences

BACKGROUND: Top-down mass spectrometry has unique advantages in identifying proteoforms with multiple post-translational modifications and/or unknown alterations. Most software tools in this area search top-down mass spectra against a protein sequence database for proteoform identification. When the...

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Detalles Bibliográficos
Autores principales: Li, Ziwei, He, Bo, Kou, Qiang, Wang, Zhe, Wu, Si, Liu, Yunlong, Feng, Weixing, Liu, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309053/
https://www.ncbi.nlm.nih.gov/pubmed/30591035
http://dx.doi.org/10.1186/s12859-018-2462-1