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β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility

BACKGROUND: β(2)-adrenergic receptors (β(2)ARs) are the target of catecholamines and play fundamental roles in cardiovascular, pulmonary, and skeletal muscle physiology. An important action of β(2)AR stimulation on skeletal muscle is anabolic growth, which has led to the use of agonists such as clen...

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Detalles Bibliográficos
Autores principales: Kim, Jihee, Grotegut, Chad A., Wisler, James W., Li, Tianyu, Mao, Lan, Chen, Minyong, Chen, Wei, Rosenberg, Paul B., Rockman, Howard A., Lefkowitz, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309084/
https://www.ncbi.nlm.nih.gov/pubmed/30591079
http://dx.doi.org/10.1186/s13395-018-0184-8