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Old age-associated phenotypic screening for Alzheimer's disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa

Alzheimer's disease (AD) is the most frequent age-associated dementia with no treatments that can prevent or slow its progression. Since age is by far the major risk factor for AD, there is a strong rationale for an alternative approach to drug discovery based upon the biology of aging. Phenoty...

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Detalles Bibliográficos
Autores principales: Fischer, Wolfgang, Currais, Antonio, Liang, Zhibin, Pinto, Antonio, Maher, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309122/
https://www.ncbi.nlm.nih.gov/pubmed/30594901
http://dx.doi.org/10.1016/j.redox.2018.101089