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MacroH2A1.2 Inhibits Prostate Cancer-induced Osteoclastogenesis through Cooperation with HP1α and H1.2
Osteoclasts are multinuclear bone-resorbing cells that differentiate from hematopoietic precursor cells. Prostate cancer cells frequently spread to bone and secrete soluble signaling factors to accelerate osteoclast differentiation and bone resorption. However, processes and mechanisms that govern t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309402/ https://www.ncbi.nlm.nih.gov/pubmed/29925860 http://dx.doi.org/10.1038/s41388-018-0356-3 |