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MacroH2A1.2 Inhibits Prostate Cancer-induced Osteoclastogenesis through Cooperation with HP1α and H1.2

Osteoclasts are multinuclear bone-resorbing cells that differentiate from hematopoietic precursor cells. Prostate cancer cells frequently spread to bone and secrete soluble signaling factors to accelerate osteoclast differentiation and bone resorption. However, processes and mechanisms that govern t...

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Detalles Bibliográficos
Autores principales: Kim, Jinman, Shin, Yonghwan, Lee, Sunyoung, Kim, Miyeong, Punj, Vasu, Shin, Hongin, Kim, Kyunghwan, Koh, Jungmin, Jeong, Daewon, An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309402/
https://www.ncbi.nlm.nih.gov/pubmed/29925860
http://dx.doi.org/10.1038/s41388-018-0356-3