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Trichostatin A Shows Transient Protection from Chronic Alcohol-Induced Reactive Oxygen Species (ROS) Production in Human Monocyte-Derived Dendritic Cells

OBJECTIVE: The objective of this study was to understand whether histone deacetylase (HDACs) inhibitor Trichostatin A or TSA can block and/or reverse chronic alcohol exposure-induced ROS in human monocyte-derived dendritic cells (MDDCs). Additionally, since nuclear factor (erythroid-derived 2)-like...

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Detalles Bibliográficos
Autores principales: Parira, Tiyash, Figueroa, Gloria, Granado, Sherly, Napuri, Jacqueline, Castillo-Chabeco, Boris, Nair, Madhavan, Agudelo, Marisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309403/
https://www.ncbi.nlm.nih.gov/pubmed/30596124
http://dx.doi.org/10.4172/2329-6488.1000316