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SYNGAP1 Heterozygosity Disrupts Sensory Processing by Reducing Touch-Related Activity within Somatosensory Cortex Circuits

In addition to cognitive impairments, neurodevelopmental disorders (NDDs) often result in sensory processing deficits. However, the biological mechanisms that underlie impaired sensory processing associated with NDDs are generally understudied and poorly understood. We found that SYNGAP1 haploinsuff...

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Detalles Bibliográficos
Autores principales: Michaelson, Sheldon D., Ozkan, Emin D., Aceti, Massimiliano, Maity, Sabyasachi, Llamosas, Nerea, Weldon, Monica, Mizrachi, Elisa, Vaissiere, Thomas, Gaffield, Michael A., Christie, Jason M., Holder, J. Lloyd, Miller, Courtney A., Rumbaugh, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309426/
https://www.ncbi.nlm.nih.gov/pubmed/30455457
http://dx.doi.org/10.1038/s41593-018-0268-0