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Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells

All mature blood cell types in the adult animal arise from hematopoietic stem and progenitor cells (HSPCs). However, the developmental cues regulating HSPC ontogeny are incompletely understood. In particular, the details surrounding a requirement for Wnt/β-catenin signaling in the development of mat...

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Detalles Bibliográficos
Autores principales: Grainger, Stephanie, Richter, Jenna, Palazόn, Raquel Espίn, Pouget, Claire, Lonquich, Brianna, Wirth, Sara, Grassme, Kathrin Sabine, Herzog, Wiebke, Swift, Matthew R., Weinstein, Brant M., Traver, David, Willert, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309681/
https://www.ncbi.nlm.nih.gov/pubmed/27806298
http://dx.doi.org/10.1016/j.celrep.2016.10.027