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Clinical Trial Designs and Measures in Hereditary Spastic Paraplegias
Hereditary spastic paraplegias (HSPs) are a large group of genetically-diverse neurologic disorders characterized clinically by a common feature of lower extremity spasticity and gait difficulties. Current therapies are predominantly symptomatic, and even then usually provide inadequate relief of sy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309810/ https://www.ncbi.nlm.nih.gov/pubmed/30627115 http://dx.doi.org/10.3389/fneur.2018.01017 |