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(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition
Protein ADP-ribosylation is a highly dynamic post-translational modification. The rapid turnover is achieved, among others, by ADP-(ribosyl)hydrolases (ARHs), an ancient family of enzymes that reverses this modification. Recently ARHs came into focus due to their role as regulators of cellular stres...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309922/ https://www.ncbi.nlm.nih.gov/pubmed/30472116 http://dx.doi.org/10.1016/j.chembiol.2018.11.001 |