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Podoplanin(+) tumor lymphatics are rate limiting for breast cancer metastasis

Metastatic dissemination employs both the blood and lymphatic vascular systems. Solid tumors dynamically remodel and generate both vessel types during cancer progression. Lymphatic vessel invasion and cancer cells in the tumor-draining lymph nodes (LNs) are prognostic markers for breast cancer metas...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Keskin, Doruk, Sugimoto, Hikaru, Kanasaki, Keizo, Phillips, Patricia E., Bizarro, Lauren, Sharpe, Arlene, LeBleu, Valerie S., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310240/
https://www.ncbi.nlm.nih.gov/pubmed/30592710
http://dx.doi.org/10.1371/journal.pbio.2005907