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Removal of heat-sensitive clustered damaged DNA sites is independent of double-strand break repair

DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ionizing radiation or radiometric drug treatment. In addition to prompt DSBs, DSBs may also be produced during repair, evolving from a clustered DNA damaged site, which is composed of two or more distinct...

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Detalles Bibliográficos
Autores principales: Abramenkovs, Andris, Stenerlöw, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310273/
https://www.ncbi.nlm.nih.gov/pubmed/30592737
http://dx.doi.org/10.1371/journal.pone.0209594