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CD71(+)VISTA(+) erythroid cells promote the development and function of regulatory T cells through TGF-β

Cell-surface transferrin receptor (CD71(+)) erythroid cells are abundant in newborns with immunomodulatory properties. Here, we show that neonatal CD71(+) erythroid cells express significant levels of V-domain Immunoglobulin (Ig) Suppressor of T Cell Activation (VISTA) and, via constitutive producti...

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Detalles Bibliográficos
Autores principales: Shahbaz, Shima, Bozorgmehr, Najmeh, Koleva, Petya, Namdar, Afshin, Jovel, Juan, Fava, Roy A., Elahi, Shokrollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310287/
https://www.ncbi.nlm.nih.gov/pubmed/30550561
http://dx.doi.org/10.1371/journal.pbio.2006649