Cargando…

Treatment with P28GST, a schistosome-derived enzyme, after acute colitis induction in mice: Decrease of intestinal inflammation associated with a down regulation of Th1/Th17 responses

BACKGROUND: P28GST, a 28Kd glutathione S-transferase enzymatic protein derived from a schistosome helminth prevents experimental colitis when administered subcutaneously in the presence of adjuvant by decreasing pro-inflammatory Th1/Th17 response. Given the antioxidant properties of P28GST, we evalu...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarazin, Aurore, Dendooven, Arnaud, Delbeke, Marie, Gatault, Solène, Pagny, Aurélien, Standaert, Annie, Rousseaux, Christel, Desreumaux, Pierre, Dubuquoy, Laurent, Capron, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310452/
https://www.ncbi.nlm.nih.gov/pubmed/30592734
http://dx.doi.org/10.1371/journal.pone.0209681