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Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex

Signaling by the G-protein-coupled receptors (GPCRs) plays fundamental role in a vast number of essential physiological functions. Precise control of GPCR signaling requires action of regulators of G protein signaling (RGS) proteins that deactivate heterotrimeric G proteins. RGS proteins are elabora...

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Detalles Bibliográficos
Autores principales: Patil, Dipak N, Rangarajan, Erumbi S, Novick, Scott J, Pascal, Bruce D, Kojetin, Douglas J, Griffin, Patrick R, Izard, Tina, Martemyanov, Kirill A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310461/
https://www.ncbi.nlm.nih.gov/pubmed/30540250
http://dx.doi.org/10.7554/eLife.42150