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Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats

OBJECTIVES: The main objective of the study was to assess the effect of age on target tissue total gadolinium (Gd) retention after repeated administration of gadodiamide (linear) or gadoterate (macrocyclic) Gd-based contrast agent (GBCA) in rats. The secondary objective was to assess the potential d...

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Detalles Bibliográficos
Autores principales: Fretellier, Nathalie, Granottier, Agnès, Rasschaert, Marlène, Grindel, Anne-Laure, Baudimont, Fannie, Robert, Philippe, Idée, Jean-Marc, Corot, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310471/
https://www.ncbi.nlm.nih.gov/pubmed/30394964
http://dx.doi.org/10.1097/RLI.0000000000000517