Regulated Capture of V(κ) Gene Topologically Associating Domains by Transcription Factories

Expression of vast repertoires of antigen receptors by lymphocytes, with each cell expressing a single receptor, requires stochastic activation of individual variable (V) genes for transcription and recombination. How this occurs remains unknown. Using single-cell RNA sequencing (scRNA-seq) and alle...

Descripción completa

Detalles Bibliográficos
Autores principales: Karki, Sophiya, Kennedy, Domenick E., Mclean, Kaitlin, Grzybowski, Adrian T., Maienschein-Cline, Mark, Banerjee, Shiladitya, Xu, Heping, Davis, Elizabeth, Mandal, Malay, Labno, Christine, Powers, Sarah E., Le Beau, Michelle M., Dinner, Aaron R., Singh, Harinder, Ruthenburg, Alexander J., Clark, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310487/
https://www.ncbi.nlm.nih.gov/pubmed/30157436
http://dx.doi.org/10.1016/j.celrep.2018.07.091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310487/
https://www.ncbi.nlm.nih.gov/pubmed/30157436
http://dx.doi.org/10.1016/j.celrep.2018.07.091

Ejemplares similares