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Regulated Capture of V(κ) Gene Topologically Associating Domains by Transcription Factories

Expression of vast repertoires of antigen receptors by lymphocytes, with each cell expressing a single receptor, requires stochastic activation of individual variable (V) genes for transcription and recombination. How this occurs remains unknown. Using single-cell RNA sequencing (scRNA-seq) and alle...

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Detalles Bibliográficos
Autores principales:	Karki, Sophiya, Kennedy, Domenick E., Mclean, Kaitlin, Grzybowski, Adrian T., Maienschein-Cline, Mark, Banerjee, Shiladitya, Xu, Heping, Davis, Elizabeth, Mandal, Malay, Labno, Christine, Powers, Sarah E., Le Beau, Michelle M., Dinner, Aaron R., Singh, Harinder, Ruthenburg, Alexander J., Clark, Marcus R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310487/ https://www.ncbi.nlm.nih.gov/pubmed/30157436 http://dx.doi.org/10.1016/j.celrep.2018.07.091

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