Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report

RATIONALE: The mechanisms of action of MTX (methotrexate) in the treatment of RA (rheumatoid arthritis) and PsA (psoriatic arthritis) is related to its antifolic activity, due to the high affinity for enzymes that require folate cofactors as dihydrofolate reductase and to the anti-inflammatory activ...

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Detalles Bibliográficos
Autores principales: Saviola, Gianantonio, Abdi-Ali, Lul, Sacco, Silvano, Comini, Laura, Plewnia, Katrin, Rossi, Maja, Orrico, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310541/
https://www.ncbi.nlm.nih.gov/pubmed/30544400
http://dx.doi.org/10.1097/MD.0000000000013350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310541/
https://www.ncbi.nlm.nih.gov/pubmed/30544400
http://dx.doi.org/10.1097/MD.0000000000013350

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