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Association between MDM2 SNP309 and endometrial cancer risk: A PRISMA-compliant meta-analysis

BACKGROUND: Murine double minute 2 homolog (MDM2) plays an important role in the downregulation of P53 tumor suppressor gene. MDM2 inhibits P53 transcriptional activity and thereby results in accelerated tumor formation. Overexpression of MDM2 has been found in several cancer types including endomet...

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Detalles Bibliográficos
Autores principales: Zou, Xinwei, Zhang, Yi, Zhang, Lin, Li, Jiaxi, Zhu, Chenjie, Cheng, Qiuhong, Zhou, Jinhua, Chen, Youguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310604/
https://www.ncbi.nlm.nih.gov/pubmed/30544386
http://dx.doi.org/10.1097/MD.0000000000013273