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Engineering Globin Gene Expression

Hemoglobinopathies, including sickle cell disease and thalassemia, are among the most common inherited genetic diseases worldwide. Due to the relative ease of isolating and genetically modifying hematopoietic stem and progenitor cells, recent gene editing and gene therapy strategies have progressed...

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Detalles Bibliográficos
Autores principales: Davis, Rachael, Gurumurthy, Aishwarya, Hossain, Mir A., Gunn, Eliot M., Bungert, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310746/
https://www.ncbi.nlm.nih.gov/pubmed/30603654
http://dx.doi.org/10.1016/j.omtm.2018.12.004