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Engineering Globin Gene Expression
Hemoglobinopathies, including sickle cell disease and thalassemia, are among the most common inherited genetic diseases worldwide. Due to the relative ease of isolating and genetically modifying hematopoietic stem and progenitor cells, recent gene editing and gene therapy strategies have progressed...
Autores principales: | Davis, Rachael, Gurumurthy, Aishwarya, Hossain, Mir A., Gunn, Eliot M., Bungert, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310746/ https://www.ncbi.nlm.nih.gov/pubmed/30603654 http://dx.doi.org/10.1016/j.omtm.2018.12.004 |
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