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Profiling proliferative cells and their progeny in damaged murine hearts

The significance of cardiac stem cell (CSC) populations for cardiac regeneration remains disputed. Here, we apply the most direct definition of stem cell function (the ability to replace lost tissue through cell division) to interrogate the existence of CSCs. By single-cell mRNA sequencing and genet...

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Detalles Bibliográficos
Autores principales: Kretzschmar, Kai, Post, Yorick, Bannier-Hélaouët, Marie, Mattiotti, Andrea, Drost, Jarno, Basak, Onur, Li, Vivian S. W., van den Born, Maaike, Gunst, Quinn D., Versteeg, Danielle, Kooijman, Lieneke, van der Elst, Stefan, van Es, Johan H., van Rooij, Eva, van den Hoff, Maurice J. B., Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310797/
https://www.ncbi.nlm.nih.gov/pubmed/30530645
http://dx.doi.org/10.1073/pnas.1805829115