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TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers

Large coat protein complex II (COPII)-coated vesicles serve to convey the large cargo procollagen I (PC1) from the endoplasmic reticulum (ER). The link between large cargo in the lumen of the ER and modulation of the COPII machinery remains unresolved. TANGO1 is required for PC secretion and interac...

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Detalles Bibliográficos
Autores principales: Yuan, Lin, Kenny, Samuel J., Hemmati, Juliet, Xu, Ke, Schekman, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310809/
https://www.ncbi.nlm.nih.gov/pubmed/30545919
http://dx.doi.org/10.1073/pnas.1814810115