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TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers
Large coat protein complex II (COPII)-coated vesicles serve to convey the large cargo procollagen I (PC1) from the endoplasmic reticulum (ER). The link between large cargo in the lumen of the ER and modulation of the COPII machinery remains unresolved. TANGO1 is required for PC secretion and interac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310809/ https://www.ncbi.nlm.nih.gov/pubmed/30545919 http://dx.doi.org/10.1073/pnas.1814810115 |