Sex-specific phenotypes of histone H4 point mutants establish dosage compensation as the critical function of H4K16 acetylation in Drosophila

Acetylation of histone H4 at lysine 16 (H4K16) modulates nucleosome–nucleosome interactions and directly affects nucleosome binding by certain proteins. In Drosophila, H4K16 acetylation by the dosage compensation complex subunit Mof is linked to increased transcription of genes on the single X chrom...

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Detalles Bibliográficos
Autores principales: Copur, Ömer, Gorchakov, Andrey, Finkl, Katja, Kuroda, Mitzi I., Müller, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310812/
https://www.ncbi.nlm.nih.gov/pubmed/30530664
http://dx.doi.org/10.1073/pnas.1817274115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310812/
https://www.ncbi.nlm.nih.gov/pubmed/30530664
http://dx.doi.org/10.1073/pnas.1817274115

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