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Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells. How mitotic recombination is prevented—and how genetic stability is maintaine...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310853/ https://www.ncbi.nlm.nih.gov/pubmed/30530674 http://dx.doi.org/10.1073/pnas.1809583115 |