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Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets

Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells. How mitotic recombination is prevented—and how genetic stability is maintaine...

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Detalles Bibliográficos
Autores principales: Hua, Lisa L., Mikawa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310853/
https://www.ncbi.nlm.nih.gov/pubmed/30530674
http://dx.doi.org/10.1073/pnas.1809583115