Model based on GA and DNN for prediction of mRNA-Smad7 expression regulated by miRNAs in breast cancer

BACKGROUND: The Smad7 protein is negative regulator of the TGF-β signaling pathway, which is upregulated in patients with breast cancer. miRNAs regulate proteins expressions by arresting or degrading the mRNAs. The purpose of this work is to identify a miRNAs profile that regulates the expression of...

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Detalles Bibliográficos
Autores principales: Manzanarez-Ozuna, Edgar, Flores, Dora-Luz, Gutiérrez-López, Everardo, Cervantes, David, Juárez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310970/
https://www.ncbi.nlm.nih.gov/pubmed/30594253
http://dx.doi.org/10.1186/s12976-018-0095-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310970/
https://www.ncbi.nlm.nih.gov/pubmed/30594253
http://dx.doi.org/10.1186/s12976-018-0095-8

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