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Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains
BACKGROUND: Pseudorabies virus (PRV) of the family Herpesviridae is the causative agent of Aujeszky’s disease. Attenuation of PRV by serial passaging in vitro is a well-established method; however, the dynamic variations occurring on viral genome during this process have not been characterized. METH...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310976/ https://www.ncbi.nlm.nih.gov/pubmed/30594230 http://dx.doi.org/10.1186/s12985-018-1102-8 |