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Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains

BACKGROUND: Pseudorabies virus (PRV) of the family Herpesviridae is the causative agent of Aujeszky’s disease. Attenuation of PRV by serial passaging in vitro is a well-established method; however, the dynamic variations occurring on viral genome during this process have not been characterized. METH...

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Detalles Bibliográficos
Autores principales: Ye, Chao, Wu, Jiqiang, Tong, Wu, Shan, Tongling, Cheng, Xuefei, Xu, Jingjing, Liang, Chao, Zheng, Hao, Li, Guoxin, Tong, Guangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310976/
https://www.ncbi.nlm.nih.gov/pubmed/30594230
http://dx.doi.org/10.1186/s12985-018-1102-8