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The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

BACKGROUND: There are some limitations of standard chemotherapy for acute leukemia. Vincristine and doxorubicin are commonly used for acute leukemia, but they may induce serious side effects such as cardiomyopathy and neurotoxicity. Furthermore, chemotherapy resistance occurs more and more frequentl...

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Detalles Bibliográficos
Autores principales: Tu, Huang-Ju, Lin, Yi-Jyun, Chao, Min-Wu, Sung, Ting-Yi, Wu, Yi-Wen, Chen, Yi-Ying, Lin, Mei-Hsiang, Liou, Jing-Ping, Pan, Shiow-Lin, Yang, Chia-Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310984/
https://www.ncbi.nlm.nih.gov/pubmed/30594243
http://dx.doi.org/10.1186/s13148-018-0595-8