Toll-Like Receptor 4–Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Shikonin Treatment of CIA by Regulating Treg/Th17 Expression

OBJECTIVE: To investigate the effect of shikonin on (CIA) collagen-induced arthritis and its influence and mechanism on the balance between Th17 cells and Treg cells. METHODS: Three doses of shikonin were administered orally to mice before the onset of CIA, and celecoxib was used as positive control...

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Detalles Bibliográficos
Autores principales: Dai, Qiaomei, Li, Ji, Yun, Yu, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311288/
https://www.ncbi.nlm.nih.gov/pubmed/30643526
http://dx.doi.org/10.1155/2018/2428546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311288/
https://www.ncbi.nlm.nih.gov/pubmed/30643526
http://dx.doi.org/10.1155/2018/2428546

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