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Toll-Like Receptor 4–Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Shikonin Treatment of CIA by Regulating Treg/Th17 Expression
OBJECTIVE: To investigate the effect of shikonin on (CIA) collagen-induced arthritis and its influence and mechanism on the balance between Th17 cells and Treg cells. METHODS: Three doses of shikonin were administered orally to mice before the onset of CIA, and celecoxib was used as positive control...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311288/ https://www.ncbi.nlm.nih.gov/pubmed/30643526 http://dx.doi.org/10.1155/2018/2428546 |