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Pathogenic Feed-Forward Mechanisms in Alzheimer’s and Parkinson’s Disease Converge on GSK-3

Alzheimer’s disease (AD) and Parkinson’s disease (PD) share many commonalities ranging from signaling deficits such as altered cholinergic activity, neurotrophin and insulin signaling to cell stress cascades that result in proteinopathy, mitochondrial dysfunction and neuronal cell death. These patho...

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Detalles Bibliográficos
Autores principales: Albeely, Abdalla M., Ryan, Scott D., Perreault, Melissa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311352/
https://www.ncbi.nlm.nih.gov/pubmed/30598867
http://dx.doi.org/10.3233/BPL-180078