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Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm

Small molecule accumulation in Gram-negative bacteria is a key challenge to discover novel antibiotics, because of their two membranes and efflux pumps expelling toxic molecules. An approach to overcome this challenge is to hijack uptake pathways so that bacterial transporters shuttle the antibiotic...

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Detalles Bibliográficos
Autores principales: Dumont, Estelle, Vergalli, Julia, Pajovic, Jelena, Bhamidimarri, Satya P, Morante, Koldo, Wang, Jiajun, Lubriks, Dmitrijs, Suna, Edgars, Stavenger, Robert A, Winterhalter, Mathias, Réfrégiers, Matthieu, Pagès, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311466/
https://www.ncbi.nlm.nih.gov/pubmed/30620010
http://dx.doi.org/10.26508/lsa.201800242