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Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

Chromatin immunoprecipitation (ChIP)-seq analyses of transcription factors in clinical specimens are challenging due to the technical limitations and low quantities of starting material, often resulting in low enrichments and poor signal-to-noise ratio. Here, we present an optimized protocol for tra...

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Detalles Bibliográficos
Autores principales: Singh, Abhishek A, Schuurman, Karianne, Nevedomskaya, Ekaterina, Stelloo, Suzan, Linder, Simon, Droog, Marjolein, Kim, Yongsoo, Sanders, Joyce, van der Poel, Henk, Bergman, Andries M, Wessels, Lodewyk FA, Zwart, Wilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311467/
https://www.ncbi.nlm.nih.gov/pubmed/30620009
http://dx.doi.org/10.26508/lsa.201800115