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Optimized ChIP-seq method facilitates transcription factor profiling in human tumors
Chromatin immunoprecipitation (ChIP)-seq analyses of transcription factors in clinical specimens are challenging due to the technical limitations and low quantities of starting material, often resulting in low enrichments and poor signal-to-noise ratio. Here, we present an optimized protocol for tra...
Autores principales: | Singh, Abhishek A, Schuurman, Karianne, Nevedomskaya, Ekaterina, Stelloo, Suzan, Linder, Simon, Droog, Marjolein, Kim, Yongsoo, Sanders, Joyce, van der Poel, Henk, Bergman, Andries M, Wessels, Lodewyk FA, Zwart, Wilbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311467/ https://www.ncbi.nlm.nih.gov/pubmed/30620009 http://dx.doi.org/10.26508/lsa.201800115 |
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