Altered Synaptic Vesicle Release and Ca(2+) Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the abnormal expansion of CAG repeats in the huntingtin (HTT) gene, which leads to progressive loss of neurons starting in the striatum and cortex. One possible mechanism for this selective loss of neurons in the early st...

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Detalles Bibliográficos
Autores principales: Chen, Sidong, Yu, Chenglong, Rong, Li, Li, Chun Hei, Qin, Xianan, Ryu, Hoon, Park, Hyokeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311661/
https://www.ncbi.nlm.nih.gov/pubmed/30618623
http://dx.doi.org/10.3389/fnmol.2018.00478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311661/
https://www.ncbi.nlm.nih.gov/pubmed/30618623
http://dx.doi.org/10.3389/fnmol.2018.00478

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