Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity

[Image: see text] Tuberculosis and parasitic diseases, such as giardiasis, amebiasis, leishmaniasis, and trypanosomiasis, all urgently require improved treatment options. Recently, it has been shown that antitubercular bicyclic nitroimidazoles such as pretomanid and delamanid have potential as repur...

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Detalles Bibliográficos
Autores principales: Jarrad, Angie M., Ang, Chee Wei, Debnath, Anjan, Hahn, Hye Jee, Woods, Kyra, Tan, Lendl, Sykes, Melissa L., Jones, Amy J., Pelingon, Ruby, Butler, Mark S., Avery, Vicky M., West, Nicholas P., Karoli, Tomislav, Blaskovich, Mark A. T., Cooper, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311682/
https://www.ncbi.nlm.nih.gov/pubmed/30468386
http://dx.doi.org/10.1021/acs.jmedchem.8b01578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311682/
https://www.ncbi.nlm.nih.gov/pubmed/30468386
http://dx.doi.org/10.1021/acs.jmedchem.8b01578

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