Cargando…

Acyl Glycosides through Stereospecific Glycosyl Cross-Coupling: Rapid Access to C(sp(3))-Linked Glycomimetics

[Image: see text] Replacement of a glycosidic bond with hydrolytically stable C–C surrogates is an efficient strategy to access glycomimetics with improved physicochemical and pharmacological properties. We describe here a stereoretentive cross-coupling reaction of glycosyl stannanes with C(sp(2))-...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Feng, Rodriguez, Jacob, O’Neill, Sloane, Walczak, Maciej A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311691/
https://www.ncbi.nlm.nih.gov/pubmed/30648149
http://dx.doi.org/10.1021/acscentsci.8b00628