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Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland

Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. We have previously shown that spontaneous tumors form frequently in mice homozygous for a full-length Brca1 deletion. In general, mutations of BRCA1 are closely associated with induction of breast...

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Detalles Bibliográficos
Autores principales: Kim, Sun Eui, Baek, Hye Jung, Park, Eun Jung, Lim, Sung Chul, Kim, Sang Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311772/
https://www.ncbi.nlm.nih.gov/pubmed/30652068
http://dx.doi.org/10.1155/2018/8120579