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Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland
Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. We have previously shown that spontaneous tumors form frequently in mice homozygous for a full-length Brca1 deletion. In general, mutations of BRCA1 are closely associated with induction of breast...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311772/ https://www.ncbi.nlm.nih.gov/pubmed/30652068 http://dx.doi.org/10.1155/2018/8120579 |