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Identification of active signaling pathways by integrating gene expression and protein interaction data
BACKGROUND: Signaling pathways are the key biological mechanisms that transduce extracellular signals to affect transcription factor mediated gene regulation within cells. A number of computational methods have been developed to identify the topological structure of a specific signaling pathway usin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311899/ https://www.ncbi.nlm.nih.gov/pubmed/30598083 http://dx.doi.org/10.1186/s12918-018-0655-x |