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Identification of active signaling pathways by integrating gene expression and protein interaction data

BACKGROUND: Signaling pathways are the key biological mechanisms that transduce extracellular signals to affect transcription factor mediated gene regulation within cells. A number of computational methods have been developed to identify the topological structure of a specific signaling pathway usin...

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Detalles Bibliográficos
Autores principales: Kabir, Md Humayun, Patrick, Ralph, Ho, Joshua W. K., O’Connor, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311899/
https://www.ncbi.nlm.nih.gov/pubmed/30598083
http://dx.doi.org/10.1186/s12918-018-0655-x